Skyjacked is a 1972 American disaster film starring Charlton Heston and Yvette Mimieux. Directed by John Guillermin, the film

is based on the David Harper novel Hijacked. James Brolin led an ensemble cast primarily playing the roles of passengers and crew aboard an airliner.

Skyjacked was the last of actress Jeanne Crain's 64 films. It was the film debut for several actors and actresses, including Susan Dey and Roosevelt "Rosey" Grier.