Casino Royale is a 2006 spy film, the twenty-first in the Eon Productions James Bond series, and the third screen adaptation of Ian Fleming's 1953 novel of the same name. Directed by Martin Campbell from a screenplay by Neil Purvis, Robert Wade, and Paul Haggis, it stars Daniel Craig in his first appearance as Bond, alongside Eva Green, Mads Mikkelsen, Judi Dench, and Jeffrey Wright. In the film, Bond is on a mission to bankrupt terrorism financier Le Chiffre (Mikkelsen) in a high-stakes poker game at the Casino Royale in Montenegro.

Following Die Another Day (2002), Eon decided to reboot the franchise, attempting to provide a realistic exploration of a less experienced and more vulnerable Bond. Casting involved a widespread search for a new actor to succeed Pierce Brosnan as Bond; the choice of Craig, announced in October 2005, initially proved controversial. Principal photography took place in the Bahamas, Italy, the United Kingdom, and the Czech Republic, with interior sets built at Pinewood Studios and Barrandov Studios. Casino Royale features primarily practical stuntwork as opposed to the computer-generated placements seen in other Bond films.

Casino Royale premiered at the Odeon Leicester Square on 14 November 2006, and was theatrically released first in the United Kingdom on 16 November, and in the United States a day later. The film received critical acclaim, with praise for Craig's reinvention of the character and the departure from the tropes of previous Bond films. It grossed over $616 million worldwide, becoming the fourth highest-grossing film of 2006 and the highest-grossing James Bond film until the release of Skyfall (2012). A sequel, Quantum of Solace, was released in 2008.