Queen Louise (German: Königin Luise) is a German silent historical film directed by Karl Grune and starring Mady Christians, Mathias Wieman, and Anita Dorris. It was released in two separate parts slightly less than a month from each other in December 1927 and January 1928. It commenced a series of historical epics directed by Grune. It was shot partly at the Terra Studios in Berlin. The film's sets were designed by the art director Hans Jacoby.

The film portrays the short life of Louise of Mecklenburg-Strelitz, wife of the Prussian monarch Frederick William III.