The Amazing Screw-On Head is a one-shot comic book written and drawn by Mike Mignola and published by Dark Horse Comics in 2002, starring the character of the same name. The Amazing Screw-On Head stars a robot living during the Lincoln administration whose head can be attached to different bodies with different tactical abilities, and who functions as an agent of the U.S. government.

The idea for the character was inspired by action figures, particularly Batman ones, which seemed to Mignola to be the same figurines with different paint jobs. Mignola imagined a robot with a head that screwed onto different bodies to suit the occasion, hence "Screw-on Head". An animated pilot, based on the plot of the comic, was produced by the Sci-Fi Channel in 2006, with Bryan Fuller as writer and executive producer and Chris Prynoski as director.