Hope for Haiti Now: A Global Benefit for Earthquake Relief was a charity telethon held on January 22, 2010, from 8 p.m. to 10 p.m. Eastern Standard Time (January 23, 2010 from 1 a.m. to 3 a.m. UTC). The telethon was the most widely distributed telethon in history. The event was broadcast from Studio 36 at CBS Television City in Los Angeles, Kaufman Astoria Studios in Queens, New York and a private club, The Hospital, in London. There were also live reports from Haiti.

Initial plans for the telethon were announced by MTV Networks on January 15, 2010, three days after the 2010 Haiti earthquake struck on January 12 that is assumed to have claimed the lives of about 200,000 people. The event was one of a number of humanitarian responses to the earthquake. Processing of the telethon's donations was in the hands of the Entertainment Industry Foundation. The telethon was patterned after the form begun with the 2001 America: A Tribute to Heroes program and continued with the 2005 Shelter from the Storm: A Concert for the Gulf Coast.

Funds raised by the telethon and from the sale of an accompanying album and video, which was immediately made available for pre-order on iTunes, were distributed to seven non-profit organizations doing relief work in Haiti.