Dylan Dog: Dead of Night is a 2011 American action horror-comedy film based on Tiziano Sclavi's Italian comic book Dylan Dog. The film was directed by Kevin Munroe, and written by Thomas Dean Donnelly and Joshua Oppenheimer. Brandon Routh stars as the eponymous antagonistic and self-aware detective who investigates cases involving the vampires, zombies, and werewolves of New Orleans. Sam Huntington, Anita Briem, Peter Stormare, and Taye Diggs are among the supporting cast.

Dylan Dog: Dead of Night was released by Omni/Freestyle Releasing in the United States on April 29, 2011. The film received negative reviews from critics, and was a box-office bomb after grossing just $5.8 million on a $20 million budget.