Comedy of Innocence (French: Comédie de l'innocence) is a 2000 French supernatural drama film directed by Chilean filmmaker Raúl Ruiz and starring Isabelle Huppert. It is co-scripted by Ruiz and Françoise Dumas. The film is produced by Mact Productions, distributed by Canal+, CNC, TF1, Les Films du Camelia. As Michael Goddard indicates in his book, The Cinema of Raul Ruiz: Impossible Cartographies, the film was loosely adapted from Massimo Bontempelli novel "Il Figlio di Due Madri", or "The Child of Two Mothers"

The music is composed by Jorge Arriagada, a Chilean composer who collaborated with Ruiz on other films such as Shattered Image and Three Lives and Only One Death, indicating a common practice for Ruiz to collaborate with the same core crew members over multiple films.