Nichols and May: Take Two is a 1996 documentary film directed by Phillip Schopper about the comedy sketch team starring Mike Nichols and Elaine May, often referred to as Nichols and May.

The documentary series premiered as part of the American Masters series PBS. Documentary about the influential comedy team known as Nichols and May, includes highlights of the team's many television appearances, featuring recently discovered kinescopes of live performances not seen since their original television broadcasts in the late 1950s and 60s. Four of their radio sketches have been re-created with new animation created especially for the program. The documentary also features insights from fellow comedians Steve Martin, Robin Williams, Richard Lewis, and Steve Allen.