The Cockeyed Cowboys of Calico County is a 1970 American comedy Western film by Universal Studios, directed by Anton Leader and Ranald MacDougall, and starring Dan Blocker and Nanette Fabray, with a supporting cast featuring: Jim Backus, Mickey Rooney, Wally Cox, Jack Elam, Noah Beery, Jr., Jack Cassidy and Don "Red" Barry. MacDougal wrote the screenplay. It was originally made as a television film but the decision was made to release it to movie theaters.

The film became Blocker's final role (besides his long-running role as "Hoss Cartwright" on Bonanza) before his death from complications from gall bladder surgery, in May 1972. In late 2010, the Encore Westerns channel began showing this film intermittently on their schedule.