Tom and Jerry: Cowboy Up! is a 2022 American animated direct-to-video Western comedy film starring Tom and Jerry, produced by Warner Bros. Animation. It is the first Tom and Jerry direct-to-video animated film in five years since 2017's Tom and Jerry: Willy Wonka and the Chocolate Factory, and a continuation of the film series. It is also the first Tom and Jerry direct-to-video animated film to feature the animation services by Renegade Animation, the studio that animated The Tom and Jerry Show (2014–21) and Tom and Jerry in New York. It was released to DVD and digital in the United States and Canada on January 25, 2022.