Saint Young Men (Japanese: 聖(セイント)☆おにいさん, Hepburn: Seinto Oniisan) is a Japanese slice of life comedy manga series written and illustrated by Hikaru Nakamura. Its plot involves Jesus Christ and Gautama Buddha, who are living as roommates in an apartment in Tokyo. It has been serialized by Kodansha in the monthly seinen manga magazine Morning Two since September 2006, with chapters collected in twenty-one tankōbon volumes as of March 2024. Kodansha USA has been publishing the series in English in an omnibus edition since December 2019. A-1 Pictures adapted the manga series into two original animation DVDs (OADs) and an anime film which was released on May 10, 2013. It also inspired a ten-episode live-action web series in 2018.

In Japan, the Saint Young Men manga has sold over 16 million copies. Individual volumes of the series have frequently appeared on lists of the weekly and annual best-seller manga in Japan. It received a Tezuka Osamu Cultural Prize in 2009 and was nominated for a Manga Taishō Award in the same year. It was also nominated for Best Comic at the 2012 Angoulême International Comics Festival. Its film adaptation has been well received by the Japanese public.