The 2022 Elimination Chamber (Arabic: إليمنيشن تشامبر; known as No Escape in Germany) was a professional wrestling event produced by the American company WWE. It was the 12th annual Elimination Chamber and took place on Saturday, February 19, 2022, at the Jeddah Super Dome in Jeddah, Saudi Arabia. The event aired via pay-per-view (PPV) and livestreaming and featured wrestlers from the promotion's Raw and SmackDown brand divisions.

It was the seventh event that WWE held in Saudi Arabia under a 10-year partnership in support of Saudi Vision 2030. It was also the first Elimination Chamber event to take place outside of the United States, the first to be held on a Saturday, and the first to livestream on Peacock. It was also WWE's first previously-established event to take place in the country.

Seven matches were contested at the event, including one on the Kickoff pre-show. The event featured two Elimination Chamber matches, one each for the men and women; both were for the Raw brand. In the main event, Brock Lesnar won the men's eponymous match to win the WWE Championship, while Bianca Belair won the women's match to earn a Raw Women's Championship match at WrestleMania 38. In other prominent matches, Becky Lynch defeated Lita to retain the Raw Women's Championship, and in the opening bout, Roman Reigns defeated Goldberg to retain SmackDown's Universal Championship.