Jess Andrews, a promising athlete with autism, was destined to be the star of a Shropshire feature film that never got finished - But the world has moved on and now an ordinary carehome receptionist called Izzy Orchard has taken her place as the face of a brand new drama series. This Comic Relief, two worlds collide as old encounters new and the Autistic Athlete with unfinished business returns to face ordinary, simple, old Izzy. Will they be able to put their differences aside to see not just each others' worth - but their own? This is Izzy Vs. Jess.

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