Muqaddar Ka Sikandar (transl. Conqueror of Destiny) is a 1978 Indian action crime drama film produced and directed by Prakash Mehra, and written by Kader Khan, Vijay Kaul and Laxmikant Sharma. It stars Amitabh Bachchan, in his fifth of nine films with Prakash Mehra, along with Vinod Khanna, Raakhee, Rekha, Ranjeet, Amjad Khan in pivotal roles, while Nirupa Roy, Kader Khan gave special appearances. The film tells of the story of Sikandar (played by Amitabh Bachchan), an orphan raised in the slums of Bombay. The film's plot is loosely inspired by the Bengali novel Devdas (1917). and the French play Cyrano de Bergerac.

Muqaddar Ka Sikandar was the highest-grossing Bollywood film of 1978, and the biggest Diwali blockbuster of all time. It was also the third highest-grossing Indian film of the decade, after Sholay and Bobby. Muqaddar Ka Sikandar was also an overseas blockbuster in the Soviet Union.

At the 26th Filmfare Awards, it was nominated for nine Filmfare Awards, including Best Film, but did not win in any category. It was remade into the Telugu film Prema Tarangalu (1980), and in Tamil as Amara Kaaviyam (1981). The movie was the last one where Amitabh Bachchan and Vinod Khanna appeared together.