Domestic Difficulties is a 1916 silent animated short film featuring Mutt and Jeff. The film is one of the earliest animated adaptations of Bud Fisher's comic strip. The film features a humorous depiction of spousal abuse.

In the film, Mutt's wife is having a night out. She makes Mutt promise to stay in their apartment, but he instead heads to a bar with Jeff. He returns intoxicated and fails to enter the apartment unnoticed. His irritated wife is waiting for him. She beats up Mutt and then defenestrates him.