Two Sons of Francisco (Portuguese: Dois Filhos de Francisco) is a 2005 Brazilian drama film about the lives of the musicians Zezé Di Camargo & Luciano, directed by Breno Silveira.

The film was one of Brazil's most successful in the last twenty years and the biggest box office draw of 2005. The film grossed the equivalent of $13 million worldwide, and a total of $8 million in Brazil, a record for Brazilian cinema. The film was selected as the Brazilian entry for the Best Foreign Language Film at the 78th Academy Awards, but it was not nominated.

Until 2008, Dois Filhos de Francisco used to be considered the second biggest audience of a Brazilian film (after the 1976 film Dona Flor and Her Two Husbands). In 2009, the blockbuster Se Eu Fosse Você 2, starring Tony Ramos and Glória Pires, replaced Dois Filhos de Francisco as the second biggest audience among the Brazilian films.