His Brother's Wife is a 1936 American romantic drama film directed by W. S. Van Dyke and starring Barbara Stanwyck and Robert Taylor. Written by Leon Gordon and John Meehan, based on a story by George Auerbach, the film is about a scientist preparing to leave for the jungles of South America to work on a cure for spotted fever. Wanting to have some fun before his trip, he goes to a gambling club where he meets and falls in love with a beautiful model while falling deep into debt. When he turns to his brother for help, his brother agrees to cover the debt, but only if he leaves without her. While the scientist is away, his brother and the model get married.

His Brother's Wife was produced by Lawrence Weingarten for Metro-Goldwyn-Mayer, and was released on August 7, 1936 in the United States. Upon its theatrical release, the film received mixed reviews that praised its expert direction and glossy production, but criticized its "outrageous implausibility". His Brother's Wife was the first of three films starring Barbara Stanwyck and Robert Taylor; the couple married in 1939.