The Musketeers of Pig Alley is a 1912 American short drama and a gangster film. It is directed by D. W. Griffith and written by Griffith and Anita Loos. It is also credited for its early use of follow focus, a fundamental tool in cinematography.

The film was released on October 31, 1912, and re-released on November 5, 1915, in the United States. The film was shot in Fort Lee, New Jersey where many other early film studios in America's first motion picture industry were based at the beginning of the 20th century. Location shots in New York City reportedly used actual street gang members as extras during the film.

It was also shown in Leeds Film Festival in November 2008, as part of Back to the Electric Palace, with live music by Gabriel Prokofiev, performed in partnership with Opera North.

In 2016, the film was added to the United States National Film Registry by the Library of Congress as being "culturally, historically, or aesthetically significant".