Francis Covers the Big Town is a 1953 American black-and-white comedy film from Universal-International, produced by Leonard Goldstein, directed by Arthur Lubin, that stars Donald O'Connor, Yvette Duguay, and Gene Lockhart. The distinctive voice of Francis is a voice-over by actor Chill Wills.

This is the fourth film in Universal-International's Francis the Talking Mule series continuing the misadventures of Peter Stirling and his friend Francis. Diabolique argued it was the best in the series.