Hollow Man is a 2000 science fiction horror thriller film directed by Paul Verhoeven, written by Andrew W. Marlowe, and starring Elisabeth Shue, Kevin Bacon, Josh Brolin, Kim Dickens, Greg Grunberg, Joey Slotnick, Mary Randle, and William Devane. The film is about Sebastian Caine, a scientist who volunteers to be the first human test subject for a serum that renders the user invisible. When his fellow scientists are unable to restore him back to normal, he becomes increasingly unstable and eventually goes on a killing spree. The film grossed $190 million worldwide but was not well received by critics. It was nominated for an Academy Award for Best Visual Effects in 2001, losing to Gladiator.

A direct-to-video stand-alone sequel called Hollow Man 2, starring Christian Slater and Peter Facinelli, was released in 2006.