Fail Safe is a 2000 televised broadcast play, based on Fail-Safe, the Cold War novel by Eugene Burdick and Harvey Wheeler. The play, broadcast live in black and white on CBS, starred George Clooney, Richard Dreyfuss, Harvey Keitel, and Noah Wyle, and was one of the few live dramas on American television since its Golden Age in the 1950s and 1960s. The broadcast was introduced by Walter Cronkite (his introduction, also broadcast in black and white, is included in the DVD releases of the film): it was directed by veteran British filmmaker Stephen Frears.

The novel was first adapted into a 1964 film of the same name directed by Sidney Lumet; the TV version is shorter than the 1964 film due to commercial airtime and omits a number of subplots.