Novocaine (known as Mr. No Pain in some regions and Novocaine No Pain in Australia) is a 2025 American action comedy film directed by Dan Berk and Robert Olsen and written by Lars Jacobson. The film stars Jack Quaid, Amber Midthunder, Ray Nicholson, Betty Gabriel, Matt Walsh, and Jacob Batalon. Its plot follows Nathan Caine (Quaid), a bank employee with the inability to feel pain who goes out to rescue his co-worker (Midthunder) after she is taken hostage by a group of bank robbers.

Novocaine was released in the United States by Paramount Pictures on March 14, 2025, to positive reviews from critics for Quaid's performance, as well as the action sequences. It has grossed $33.6 million worldwide on a budget of $18 million.