Æon Flux is an American avant-garde science fiction adventure animated television series that aired on MTV from November 30, 1991, until October 10, 1995, with film, comic book, and video game adaptations following thereafter. It premiered on MTV's Liquid Television experimental animation show, as a six-part serial of short films, followed in 1992 by five individual short episodes. In 1995, a season of ten half-hour episodes aired as a stand-alone series. Æon Flux was created by American animator Peter Chung. Each episode's plot has elements of social science fiction, biopunk, allegory, dystopian fiction, spy fiction, psychological drama, postmodern visual, psychedelic imagery and Gnostic symbolism.

The live-action movie Æon Flux, loosely based upon the series and starring Charlize Theron, was released in theaters on December 2, 2005, preceded in November of that year by a tie-in video game of the same name based mostly on the movie but containing some elements of the original TV series.