The National Museum of African American History and Culture (NMAAHC) is a Smithsonian Institution museum located on the National Mall in Washington, D.C., in the United States. It was established in December 2003 and opened its permanent home in September 2016 with a ceremony led by President Barack Obama.

Early efforts to establish a federally owned museum featuring African-American history and culture can be traced to 1915, although the modern push for such an organization did not begin until the 1970s. After years of little success, a much more serious legislative push began in 1988 that led to authorization of the museum in 2003. A site was selected in 2006, and a design submitted by Freelon Group/Adjaye Associates/Davis Brody Bond was chosen in 2009. Construction began in 2012 and the museum completed in 2016.

The NMAAHC is the world's largest museum dedicated to African-American history and culture. It ranked as the fourth most-visited Smithsonian museum in its first full year of operation. The museum has more than 40,000 objects in its collection, although only about 3,500 items are on display. The 350,000-square-foot (33,000 m2), 10 story building (five above and five below ground) and its exhibits have won critical praise.