Python (theatrically released in the Philippines as Anaconda 2000) is a 2000 made-for-TV horror film directed by Richard Clabaugh. The film features several cult favorite actors, including William Zabka of The Karate Kid fame, Wil Wheaton, Casper Van Dien, Jenny McCarthy, Keith Coogan, Robert Englund, Dana Barron, David Bowe, and Sean Whalen.

The film concerns a genetically engineered snake, a python, that escapes and unleashes itself on a small town. It was filmed in Los Angeles and Malibu, California.

Python was followed by three sequels: Pythons 2 (2002), New Alcatraz (also known as Boa) and Boa vs. Python (2004), all of which are also made-for-TV films.