Brotherhood is an American crime drama television series created by Blake Masters about the intertwining lives of the Irish-American Caffee brothers from Providence, Rhode Island: Tommy (Jason Clarke) is a local politician and Michael (Jason Isaacs) is a gangster involved with New England's Irish Mob. The show also features their mother Rose (Fionnula Flanagan), cousin Colin Carr (Brían F. O'Byrne), childhood friend and Rhode Island state detective Declan Giggs (Ethan Embry), Irish mob boss Freddie Cork (Kevin Chapman), Tommy's wife Eileen (Annabeth Gish), and Michael's criminal partner Pete McGonagle (Stivi Paskoski).

Brotherhood was originally broadcast by the premium cable network Showtime in the United States from July 9, 2006, to December 21, 2008, with the show's three seasons consisting of eleven, ten and eight episodes. The show was not renewed after its third season, which Showtime later confirmed was the last.

The series was produced and almost entirely written by Masters and Henry Bromell. It was filmed on location in Providence, Rhode Island.

Brotherhood received widespread critical acclaim—with critics particularly praising Masters and Bromell's nuanced writing and the central performances of Clarke and Isaacs—but did not attract a large audience. The show won a Peabody Award.