The Big Gay Sketch Show is an LGBT-themed sketch comedy program that debuted on Logo on April 24, 2007. The series is produced by Rosie O'Donnell and directed by Amanda Bearse. The program was originally titled The Big Gay Show but was renamed during production. As the name indicates, the show features comedy sketches with gay themes or a gay twist. Sketch topics include parodies of old sitcoms like The Honeymooners and The Facts of Life under the Nick at Nite-parodying heading "Logo at Nite", a lesbian speed dating session, and an extended send-up of Broadway legend Elaine Stritch working as a Wal-Mart greeter, among other decidedly un-glamorous jobs.

Logo produced a second season of the series. Paolo Andino and Colman Domingo joined the cast (replacing Michael Serrato and Dion Flynn). Season 2 premiered on February 5, 2008.Production on season three began in March 2009, with Erica Ash no longer part of the cast. In 2009, Logo conducted a search for new cast members. However, the result, entitled "The Big Gay Casting Competition", was limited to an online talent search, in which videos by contestants were uploaded to logoonline.com and voted on by site visitors. The winner, Wil Heuser, was a former American Idol contestant and Big Brother cast member (season 14), and only appeared in one episode of the series as an extra. The third, and so far final season was broadcast in 2010.