High Stakes Poker is an American cash game poker television program. The poker variant played on the show is no limit Texas hold 'em. The first four seasons ran from January 16, 2006 to December 17, 2007 on GSN. The next three seasons ran from March 1, 2009 to May 21, 2011, and was simulcast in 3DTV on N3D. The show was revived on December 16, 2020 on PokerGO.

The show was hosted by A. J. Benza in the first five seasons, alongside Gabe Kaplan. In the sixth season, Kara Scott replaced Benza as Kaplan's co-host, with Scott conducting interviews from the poker room floor. In the seventh season, Norm Macdonald replaced Kaplan as Scott's co-host. Beginning with the eighth season, Benza and Kaplan returned as hosts. After the first episode of the tenth season, Kaplan retired and was replaced by Nick Schulman.