La familia P. Luche (English: The P.Lush Family) is a Mexican family sitcom created by Eugenio Derbez. The series aired from August 7, 2002, to September 16, 2012, on the channel Canal de las Estrellas. It is a spin-off of a regular sketch on the XHDRbZ comedy-sketch program.

In the series, the characters live in a fictional city called "Ciudad P. Luche" where clothes and other objects are wrapped in plush. The word P. Luche, is a pun to the word plush in Spanish: peluche. The show is similar in style to the American sitcom Married... with Children, in that it depicts a comically dysfunctional family. La familia P. Luche, however, plays more like a live-action cartoon, complete with colorful sets and comic sound effects. The sitcom won a TVyNovelas Award for "Best Comedy Program" in 2008.