The World Series of Blackjack is a televised blackjack tournament created and produced by the cable network GSN. It is a closed tournament; players are either invited to play or attempt to win a spot via a satellite tournament. Rounds are edited into 1-hour episodes and broadcast on GSN. Matt Vasgersian and Max Rubin provided commentary for the first two seasons. Tiki Arsenault was the dealer for Season 1 as Deanna Bacon was the dealer for Seasons 2 and 3 while Jessica Knight was the dealer for Season 4.

Season 1 premiered weekly from March 15, 2004 to April 26, 2004 with a co-host, Melana Scantlin.

Season 2 premiered weekly from January 21, 2005 to April 22, 2005 with a new co-host, Megan Riordan.

Season 3 premiered weekly from June 5, 2006 to September 4, 2006 as part of GSN's Casino Night (retooled, with High Stakes Poker, as Vegas Night) programming block, with new hosts John Fugelsang and Ben Mezrich.

Season 4 premiered on GSN from June 4, 2007 to August 27, 2007. A field of 40 players, including Celebrity Blackjack champion Caroline Rhea, baseball star Orel Hershiser and magician Penn Jillette competed for a $1 million prize pool. Vasgersian returned as a commentator.