The Knick is an American period medical drama television series on Cinemax created by Jack Amiel and Michael Begler and directed by Steven Soderbergh. The series follows Dr. John W. Thackery (Clive Owen) and the staff at a fictionalized version of the Knickerbocker Hospital (the Knick) in New York City during the early twentieth century. Amiel and Begler wrote the majority of the episodes and are executive producers. Owen, Soderbergh, Gregory Jacobs, and Michael Sugar (Anonymous Content) were executive producers.

The ten-episode first season of The Knick premiered on Cinemax on August 8, 2014. Another season, also ten episodes long, followed on October 16, 2015. In March 2017, Cinemax announced the series was canceled. In 2020, Soderbergh confirmed that a new season of The Knick was in development led by Barry Jenkins, and that Amiel and Begler have written a pilot episode. In 2023, Begler confirmed that a spin-off series was still in development, with the pilot set in 1919 Harlem.