Señora Acero, also known as Señora Acero: La Coyote as of season three, is an American telenovela created by Roberto Stopello and produced by Argos Comunicación and Telemundo Studios, and distributed by Telemundo Internacional. The series debuted on American broadcast channel Telemundo on 23 September 2014, and concluded on 29 January 2019.

Set and filmed in Mexico, Seasons 1 and 2 tell the story of Sara Aguilar (Blanca Soto), a young housewife, who in an effort to protect her son and her friends, becomes the most powerful drug trafficker in all of Mexico. Seasons 3 through 5 focus on the life of Vicenta "La Coyote" Rigores (Carolina Miranda), a young female coyote who discovers that she is the illegitimate daughter of Vicente Acero and joins the world of drug traffickers along with her half-brother Salvador Acero (Michel Duval) to help immigrants and fight injustice.

On 20 February 2018, Telemundo confirmed that the show was renewed for a fifth season. On 8 November 2018, it was announced that the fifth season would be the show's final season.