Frangela is a Los Angeles-based comedy duo composed of comedians Frances Callier and Angela V. Shelton, both of The Second City.

Callier and Shelton regularly appeared on the VH1 weekly comedy news review Best Week Ever, the NPR radio show Day to Day and the Fox News late night show Red Eye w/Greg Gutfeld. They had their own show on KTLK called The Week According to Frangela, which aired live on Saturdays from 5:00 PM to 7:00 PM Eastern Standard Time. The comedy duo also appeared in the 2009 movie He's Just Not That Into You. Angela Shelton has voiced in Spider-Man 2 and Ultimate Spider-Man, Superman, and Reservoir Dogs video games, while Frances Callier played Roxy on the show Hannah Montana. In 2010, KTLK announced that they would be discontinuing The Week According to Frangela in favor of other local programming. The duo then moved the show to a self-distributed podcast recorded live Saturday nights at The Second City Training Center in Hollywood. On August 20, 2010, the duo recorded their final installment of the show. In February 2009, Frangela had a one-week tryout for a show on "Green 360" KKGN in San Francisco in the 4 pm-7 pm PST slot, but it was not picked up as a regular show. On September 10, 2018, the comedy duo announced the release of their debut comedy album RESIST! out October 19, 2018, on Kill Rock Stars. In 2019, the comedy duo competed in the reality television competition series Bring the Funny.