The American Bible Challenge is an American biblical-themed television game show created by Game Show Network. The series is hosted by comedian Jeff Foxworthy, with gospel musician Kirk Franklin joining Foxworthy as co-host and announcer in the second season. The series debuted on August 23, 2012.

Each season of the series is played as a nine-episode tournament with six episodes of opening rounds, two semi-finals, and a final. Each opening round starts with three teams of three contestants answering questions about the Bible. The teams then nominate their strongest contestants to answer questions by themselves without any assistance from their teammates. After this part of the round, the third-placed team is eliminated and the two highest-scoring teams compete in a final round with the scores being reset to zero. The remaining teams answer as many questions correctly as possible within one minute, and the highest-scoring team from this round wins a $20,000 prize which is given to the team's nominated charity. The winning team then advances to a semi-final game against two other winning teams, the winning team from this game advances to a final game where the grand prize is raised to $100,000. Thus, the team that wins the season-long tournament earns a total of $140,000 for their charity.

The show became the highest-rated original program in the history of the Game Show Network. In 2014, The American Bible Challenge received two nominations at the 41st Daytime Emmy Awards: one for the series as Outstanding Game Show and the other for Foxworthy as Outstanding Game Show Host, they lost to Jeopardy! and Steve Harvey (host of Family Feud) respectively.