Senhora do Destino (English: Lady of the Destiny) is a Brazilian telenovela that was produced and aired by Rede Globo from June 28, 2004, to March 11, 2005, with a total of 221 episodes. Replacing Celebridade and being replaced by América. Written by Aguinaldo Silva with the collaboration of Filipe Miguez, Gloria Barreto, Maria Elisa Berredo, and Nelson Nadotti. Directed by Luciano Sabino, Marco Rodrigo, Claudio Boeckel, with general and core direction of Wolf Maya. Nazaré Tedesco, Renata Sorrah's character, is the great villain of the plot and entered the history of Brazilian television drama as one of the best-known and cruel villains of Brazilian soap operas.

Featured Suzana Vieira, José Wilker, Carolina Dieckmann, Eduardo Moscovis, Letícia Spiller, José Mayer, Leonardo Vieira, Débora Falabella, Marcello Antony, Dan Stulbach, Tania Khalill, Carol Castro, Dado Dolabella, Marília Gabriela, José de Abreu, Leandra Leal and Renata Sorrah in leading roles.