MPD Psycho (full title Multiple Personality Detective Psycho – Kazuhiko Amamiya Returns) is a 2000 Japanese six-episode horror crime television series based on the manga of the same name and directed by Takashi Miike. It originally aired on 2 May 2000. It has a surrealist bent, and, according to Jim Harper, the author of Flowers from Hell, "bears little similarity to the average made-for-TV detective thriller".

The plot is similar to the beginning of the manga series but does not relate to the incidents of Lucy Monostone and the Gakuso Company. The story takes place in the final days of the Shōwa Era. Yosuke Kobayashi, a detective assigned to a homicide unit, saw his wife killed by a serial killer, Shinji Nishizono. From the shock of the incident, he suffers from multiple personality disorder and becomes Kazuhiko Amamiya. Soon after, he manages to hunt down and kill his wife's murderer. Now a series of murders has started and the suspect is claiming to be Shinji Nishizono.