Destroy Build Destroy is an American live action reality series on Cartoon Network hosted by Andrew W.K. It was a game show, in which two teams destroyed a random object and built vehicles from it, and then the winners destroyed the losers' creation. The series originally premiered as part of a line of live-action reality series called CN Real, which aired in 2009. The series premiered on June 20, 2009, and ended its run on September 21, 2011.

Destroy Build Destroy is one of only two shows from the CN Real block (the other being Dude, What Would Happen) to have been renewed for additional seasons, as the other CN Real shows had already been cancelled earlier, due to critically negative reception.