All Creatures Great and Small is a television series set in 1930s and 1940s Northern England, based upon a series of books about a Yorkshire veterinary surgeon written by Alf Wight under the pen name of James Herriot. The series, produced by Playground Entertainment for Channel 5, is a new adaptation of Wight's books, following the previous BBC series of 90 episodes that ran from 1978 to 1990 and a number of other films and television series based on Herriot's novels. It was filmed in the Yorkshire Dales, and received funding from Screen Yorkshire.

The first series, which consists of six episodes and a special Christmas episode, was filmed to coincide with the 50th anniversary of the publication of the first book in the James Herriot series. The series premiered in the UK on Channel 5 on 1 September 2020. Following a second series in late 2021, in January 2022 the programme was renewed for two further series, each comprising six episodes and a Christmas special. Filming on the third series began in March 2022. The first episode aired in the UK on 15 September 2022 and in the US on 8 January 2023. The fourth series began airing on 5 October 2023 in the UK and on 7 January 2024 in the US. The fifth series began airing on 19 September 2024 in the UK.

On 23 February 2024, PBS announced that the series had been renewed for a fifth and sixth series, and that Callum Woodhouse would return as Tristan Farnon.