Mike, Lu & Og is an animated television series created by Mikhail Shindel, Mikhail Aldashin, and Charles Swenson for Cartoon Network, and the 7th of the network's Cartoon Cartoons. The series follows a foreign exchange student from Manhattan named Mike, a self-appointed island princess named Lu, and a boy-genius named Og. The trio take part in various adventures as Mike and the island's natives share their customs with each other.

Before its cancellation, fifty-two eleven-minute episodes were produced by Mikhail Shindel's Kinofilm Animation in Los Angeles and animated by Mikhail Aldashin at Studio Pilot in Russia, featuring two stories per episode. The series features voice actors Nika Futterman as Mike, Nancy Cartwright as Lu, and Dee Bradley Baker as Og. The distinctive animation style is similar to shows produced by Klasky Csupo for Nickelodeon, such as Rugrats, Aaahh!!! Real Monsters, The Wild Thornberrys, Rocket Power, As Told by Ginger, and Duckman (produced for the USA Network), due to its crudely-drawn look.

Reruns were broadcast on Boomerang from 2006 to 2011. On November 6, 2017, the series was added to Cartoon Network on Demand. as well as on Max in some regions.