The Jenny Jones Show is an American first-run syndicated talk show hosted by television presenter Jenny Jones. Taped in Chicago, Illinois, the show ran for twelve seasons from September 16, 1991, to May 21, 2003. Conceived as an alternative to the sensational tabloid talk shows of the early 1990s, the show's first season focused on celebrity interviews and lifestyle segments. Following mild ratings, the show shifted to a new format for its second season; it centered on interviews with ordinary people. Episodes typically involved one topic, which was discussed among a panel of guests who had varying viewpoints. These discussions were moderated by Jones, who allowed studio audience members the opportunity to ask questions and give advice to the guests. The Jenny Jones Show frequently featured live musical performances from artists of various genres.

The Jenny Jones Show was produced by Telepictures Productions and distributed by Warner Bros. Television Studios. A former stand-up comedian, Jones was approached by Warner Bros. Television Studios with an offer to host a talk show after producers watched her "Girl's Night Out" comedy show. The show debuted on 178 television stations nationwide, which was the largest launch in syndicated talk show history. The Jenny Jones Show was one of the highest-rated talk shows of the nineties. It received the Excellence in Media’s Silver Angel Award and two SHINE Awards. However, the show also received criticism from media commentators and audiences over claims that it exploited its guests. Common topics discussed on the show included makeovers and out-of-control teenagers.

In 1995, The Jenny Jones Show experienced controversy after a former guest murdered another three days after they were featured in a taping of the show. Titled "Revealing Same Sex Secret Crush", the episode depicted self-proclaimed secret admirers revealing their crushes to guests. Jones was required to testify at the ensuing criminal trial, which received wide coverage by the news media. In 1996, the victim's family filed a negligence lawsuit against The Jenny Jones Show. The litigation resulted in a national media frenzy, with criticism directed at the use of "ambush" tactics by tabloid talk shows. It additionally resulted in a national debate over shock value and tabloid television in the United States. The Jenny Jones Show ultimately prevailed in the suit, in which the court held that the guest's actions following their appearance on the program were unforeseeable.