Anne Rice's Interview with the Vampire, or simply Interview with the Vampire, is an American gothic horror television series developed by Rolin Jones for AMC, based on The Vampire Chronicles by Anne Rice, named after the first book. Starring Jacob Anderson as Louis de Pointe du Lac and Sam Reid as Lestat de Lioncourt, it begins with the vampire Louis recounting his past and tumultuous relationship with the vampire Lestat.

The series embraces the queer elements of Rice's work, which are only insinuated in the 1994 film adaptation, and deals with themes such as race and abuse. It is the first series set in the Immortal Universe, a shared universe based on Rice's novels. A series order was made in June 2021, after AMC Networks purchased the rights to intellectual property encompassing 18 of Rice's novels in 2020.

The series premiered on October 2, 2022, with the first two seasons covering the eponymous novel. In June 2024, the series was renewed for a third season, to cover the second book The Vampire Lestat. The series received positive reviews, with praise for its writing, costumes, soundtrack, production design, lead performances and their chemistry. It has received nominations at the Critics' Choice Television Awards and GLAAD Media Awards among others.