The Barbara Vine Mysteries is a British television mystery drama series, principally written by Sandy Welch and Jacqueline Holborough and directly solely by Tim Fywell, that first broadcast on BBC1 on 10 May 1992.

Adapted from a series of novels written by Ruth Rendell under the pseudonym of Barbara Vine, the series was the BBC's attempt to rival ITV's ratings winner The Ruth Rendell Mysteries, which was set to lose its lead actor, George Baker, in the same year. Three series were broadcast, with the final episode broadcasting on 3 January 1994, shortly before The Ruth Rendell Mysteries went back into production, adapting Rendell's novels without the character of Inspector Wexford for the first time.

Certain aspects of each of the novels were modified for their television adaptations; the most notable of these being A Dark-Adapted Eye, which saw its storyline significantly altered, including the introduction of an entirely new character, an Italian lawyer played by Ciarán Hinds, who does not feature in the book. All three series were released as a complete box set via 2|Entertain DVD on 31 October 2005.