Dude, What Would Happen is an American live-action reality series that aired on Cartoon Network originally as part of its CN Real block, which aired a line of live-action reality shows promoted in the summer of 2009. The show premiered on August 19, 2009, preceded by another CN Real series Bobb'e Says. The show is hosted by three male teenagers (C.J. Manigo, Jackson Rogow, and Ali Sepasyar) who wondered what would happen if some wild event, scheme or experiment were to occur. The three teens attempt to create the event themselves and consult experts ("The Lab Dudes") when needed.

The series went on to have three seasons aired throughout a span of two years, in which the series eventually ended in September 2011, as the series was not announced for a renewal by Cartoon Network.

Dude, What Would Happen was one of only two CN Real shows (the other being Destroy Build Destroy) to have been renewed for additional seasons, as the other CN Real shows had already been cancelled earlier due to critically negative reception.