Gēmusetto (stylized as ゲームセット) is an American adult animated series created by Max Simonet, that premiered on April 1, 2019 on Adult Swim. The first season, titled Gēmusetto Machu Picchu (stylized as ゲ–ムセット Machu Picchu), follows the exploits of Makasu, a sportsman and relic thief, who constantly challenges the gods of several different religions for their relics, and his companion Back Pocket Dimension Flying Bear, on their quest to gain the treasures of the Inca-gods all the while he is chased by Bendy Rivers, a member of Interpol tasked with stopping Makasu.

The first season parodies anime-style shows, intentionally using rather strange and amateurish animation, constantly shifting quality in drawing-style, as well as rather off-beat and crass humor. The program also features several other segments in between "episodes" and parts such as alternate openings for each part, educational material regarding the different Inca-gods, flashback-segments of past challenges Makasu has faced, and fake toy-commercials promoting the program.

The series was renewed for a 14-episode second season, titled Gēmusetto: Death Beat(s) (stylized as ゲームセッ2 death beat(s)), which premiered on November 8, 2020 on Adult Swim's Toonami programming block. The second season was first revealed on April 1, 2020, as a brief clip of the season premiere was shown before leading into the night's April Fools prank. This season has a more conventional 11-minute runtime per episode as part of the Toonami block.