Mr. Lucky is a CBS adventure/drama television series that aired from 1959 to 1960. The title character, played by John Vivyan, was an honest professional gambler who used his plush floating casino, the ship Fortuna, as his base of operations. His good friend Andamo helped him run the casino.

Blake Edwards developed the program as a retooling of his Willie Dante character from Four Star Playhouse, in which the role of a former gambler who operates Dante's Inferno, a San Francisco, California, nightclub, was played by Four Star studio boss Dick Powell.

Edwards directed and co-wrote the first episode of Mr. Lucky, and the credits of the first eighteen episodes included the text, "Entire production supervised by Blake Edwards." Jack Arnold (director of Creature from the Black Lagoon, The Incredible Shrinking Man, and It Came from Outer Space) produced the show and directed fifteen of the thirty-four episodes.

Henry Mancini's smooth theme music for the show reached Number 21 in the US singles charts. He released two successful LP's based on the show, Mr. Lucky and Mr. Lucky Goes Latin.