Orphan Black is a Canadian science-fiction thriller television series created by screenwriter Graeme Manson and director John Fawcett and starring Tatiana Maslany. The series focuses on Sarah Manning, one of several genetically identical human clones, and later on some of the other clones. The series raises issues about the moral and ethical implications of human cloning and its effect on identity.

The series was produced by Temple Street Productions in association with BBC America and Bell Media's Space. The show premiered on March 30, 2013, on Space in Canada, and on BBC America in the United States. On June 16, 2016, the series was renewed for a fifth and final ten-episode season, which ran from June 10 to August 12, 2017. An aftershow, After the Black, began airing in the third season on Space and was acquired by BBC America for the fourth season. In April 2022, a spin-off titled Orphan Black: Echoes was announced, which premiered in June 2024 on AMC.

Orphan Black developed a loyal online fan base across social media platforms who identify as #CloneClub, a reference to those who are in-the-know in the story. Throughout its run, the series received critical acclaim and various accolades, particularly for Maslany's performance, which earned her a Primetime Emmy Award, two Critics' Choice Television Awards and two further nominations, one TCA Award and one further nomination, two Satellite Award nominations, and a Golden Globe Award and Screen Actors Guild Award nomination. The series won a Peabody Award in 2013 and has been nominated for, and won, several Canadian Screen Awards.