Thirumathi Selvam (Mrs. Selvam) is a 2007 Tamil television soap opera directed by S. Kumaran and produced by Radhika Srinivasan & B. Srinivasan for Vikatan Televistas. It stars Sanjeev and Abitha in the lead roles with Rindhya, Gautami and Vadivukkarasi played supporting roles. It premiered on 5 November 2007 and initially aired weekday afternoons on Sun TV, before being moved to 8PM on 1 December 2008. The serial ended on 22 March 2013 with 1360 episodes. Thirumathi Selvam is currently re-airing on Kalaignar TV from 29 March 2021.

The story revolved around the lead character Selvam and showed how his good qualities, hard work, and love for his wife Archana and care for his best friend Nandhini and how that made him reach great heights. Then, it showed how money, fame, and power led to his downfall.

The serial was remade in Hindi as Pavitra Rishta under Balaji Telefilms and it was aired on Zee TV.