Santa Clarita Diet is an American horror sitcom television series created by Victor Fresco for the streaming service Netflix, starring Drew Barrymore and Timothy Olyphant. Fresco serves as the showrunner, and is an executive producer alongside Barrymore, Olyphant, Aaron Kaplan, Tracy Katsky, Chris Miller, Ember Truesdell and Ruben Fleischer. The series centers on husband and wife real estate team Joel and Sheila Hammond whose normal, mundane lives change dramatically when Sheila shows symptoms of having become a zombie. The bewildered family seek a cure for her condition while dealing with its consequences, such as Sheila's new craving of human flesh and radically altered personality that has become more primal and impulsive.

The single-camera series premiered on February 3, 2017. The first season, consisting of 10 episodes, received generally positive reviews. On March 29, 2017, it was announced that Netflix renewed the series for a second season, which premiered on March 23, 2018. On May 8, 2018, the series was renewed for a 10-episode third season and premiered on March 29, 2019. The series was cancelled after three seasons on April 26, 2019.