Pablo y Andrea is a Mexican children's telenovela produced by Lucero Suárez for Televisa in 2005. Pablo y Andrea is an adaptation of the classic The Adventures of Tom Sawyer by Mark Twain. The adventures are not developed on the coast of the Mississippi River, but in the magical town of Huasca de Ocampo in the Mexican state of Hidalgo.

It was the last children's telenovela produced by Televisa, the lack of interest of the public with novels generated lower-rated audience. Scenes were cut from the original broadcast in order to reduce the 100 episodes to 75 because of the low ratings.

On August 1, 2005, Canal de las Estrellas started broadcasting Pablo y Andrea weekdays at 4:00pm, replacing Sueños y caramelos. The last episode was broadcast on November 11, 2005 with Peregrina replacing it.

Marcia Coutiño and Guillermo Capetillo starred as adult protagonists, Danna Paola and Jorge Trejo starred as young protagonists, while Mercedes Molto, Eduardo Rivera, María Fernanda Núñez, Adrián Alonso, Valentina Cuenca and Geraldine Galván starred as antagonists.