Mula sa Puso (English: From the Heart) is a 1997 Philippine primetime melodrama romance television series originally aired by ABS-CBN from March 10, 1997 to April 9, 1999 and was replaced by Saan Ka Man Naroroon. Claudine Barretto, Rico Yan, and Diether Ocampo played the roles of the main protagonists in the series. It was re-aired in 2008 through Studio 23 and Kapamilya Channel, which are both ABS-CBN subsidiaries. A 2011 remake, starring Lauren Young, JM de Guzman and Enrique Gil, aired on ABS-CBN from March 28 to August 12, 2011.

The show also gave critical acclaim to director Wenn V. Deramas as his first prime time soap project and as a director and gave character actress Princess Punzalan critical acclaim for her character as Selina Pereira-Matias, the main antagonist of the series. Mula sa Puso is regarded as the first middle-class-themed Filipino primetime TV drama. It was also known for being the most competitive TV series in the country's TV ratings by mid-1998, alongside Esperanza, which also ran from 1997 to 1999; the popularity of the two teleseryes spawned two films both released in 1999 (Mula sa Puso in February and Esperanza in December), and a joint soundtrack entitled "Mula Sa Puso ni Esperanza". The TV series had various crossovers with prime time dramas such as Esperanza and the short-lived miniseries Sa Sandaling Kailangan Mo Ako. The show was aired from Mondays to Fridays at 6:30 pm (March 10, 1997 until January 1, 1999) and later at 7 pm (January 4 until April 9, 1999) after TV Patrol.

The story depicts on the life of Via and as she gracefully turns 18, she will discover she lives a life full of deceit. She will also discover the truth about the identities of her loved ones and the unstoppable troubles when it comes to love and life itself as she falls in love with her savior Gabriel while she also falls into a love triangle with her persistent longtime childhood friend Michael.

It is best known for the bus explosion scene, which was its highest-viewed episode and has been deemed by viewers as iconic and remains to be referenced in Philippine pop culture today. Episode 366, which can now also be seen on Youtube, depicted a terrorist attack plotted by Selina (Princess Punzalan) in order to get rid of Via (Claudine Barretto) for good. Her henchmen planted a bomb inside the bus that was originally ridden by Via. A few minutes later, bomb exploded and killed several people, and it was initially thought that Via was among the dead; Selina is seen at the background, maniacally laughing after also thinking that Via was killed in the attack. However, it would later be revealed that Via survived as she left the bus to go to the restroom. In an ironic turn of events, the scene was originally aired on the same day of an actual terrorist attack elsewhere – the 1998 United States embassy bombings in Kenya and Tanzania.

The series is currently streaming on Jeepney TV's YouTube Channel everyday at 3:00 pm & 3:30 pm, right after Marinella.